Titolo:  Mild Synthetic Approach to Novel Indole-1-Carbinols and Preliminary Evaluation of Their Cytotoxicity in Hepatocarcinoma Cells
Data di pubblicazione:  2012
Abstract:  A mild and versatile method for the synthesis of some novel indole-1-carbinols has been developed via one-pot reaction of indoles and paraformaldehyde in the presence of an excess of CaO, MgO, ZnO or TiO2. The solvent-free reaction provided all the indole derivatives in moderate to good yields and short reaction times. Moreover, the effect of some selected indole-1-carbinols on cell proliferation of the hepatoma cell line FaO was evaluated.
Handle:  http://hdl.handle.net/11584/40798
Tipologia: 1.1 Articolo in rivista

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