Titolo:  Dopaminergic D-1 receptors: essential role in morphine-induced hypermotility
Data di pubblicazione:  1987
Abstract:  Administration of morphine HCl (20 mg/kg SC) to male C57Bl/6 mice evoked hypermotility. Pretreatment with low doses of the specific D-1 antagonist SCH 23390 (0.006, 0.012, 0.025 mg/kg SC) dose-dependently inhibited morphine-evoked hypermotility. The results suggest that dopamine is the essential mediator of opiate hypermotility and indicate that D-1 receptors play an important role in this effect.
Handle:  http://hdl.handle.net/11584/95758
Tipologia: 1.1 Articolo in rivista

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