Titolo:  Role of substantia nigra pars reticulata neurons in the expression of neuroleptic-induced catalepsy
Autori: 
Data di pubblicazione:  1981
Rivista: 
BRAIN RESEARCH  
Citazione:  Role of substantia nigra pars reticulata neurons in the expression of neuroleptic-induced catalepsy / Morelli M; Porceddu M L; Imperato A; Di Chiara G. - In: BRAIN RESEARCH. - ISSN 0006-8993. - 217:2(1981), pp. 375-379.
Abstract:  Bilateral kainate-induced lesions of the substantia nigra prevented or dramatically reduced the catalepsy produced by haloperidol. In contrast, infusion of 1 or 4 micrograms 6-OHDA in the medial forebrain bundle, which decreased striatal DA by 30% and 80% respectively, failed to affect or actually potentiated haloperidol catalepsy. Since intranigral kainate, in contrast to 6-OHDA, destroys pars reticulata neurons it appears that these neurons are essential for the expression of haloperidol-catalepsy.
Handle:  http://hdl.handle.net/11584/109434
Tipologia: 1.1 Articolo in rivista

File in questo prodotto:
Non ci sono file associati a questo prodotto.

Questionario e social

Condividi su: