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Second Semester 
Teaching style
Lingua Insegnamento

Informazioni aggiuntive

Course Curriculum CFU Length(h)
[60/56]  INDUSTRIAL BIOTECHNOLOGY [60/56-00 - Ord. 2014]  PERCORSO COMUNE 7 68


Knowledge and understanding: The course aims to provide the basic knowledge and understanding related to industrial chemistry with particular reference to the principles of thermodynamics, kinetics, catalysis, reaction mechanism, the knowledge of which are important for the realization and the conduction of chemical and biotechnological processes applied to industry for sustainable development .
Applying knowledge and understanding: the student will be able to apply their knowledge and understanding in the management of industrial biotechnology processes. Make the balance of matter and energy of simple processes, solve elementary problems of heat exchange.
Making judgments: students will be able to independently gather and interpret scientific data derived from laboratory measurements, to conduct an experiment with the evaluation and quantification of the results.
Communication skills: the student will be able to conduct experiments together; draw up a report on the activities of the laboratory using the write processor and / or graphics and the most common spreadsheet programs.
Learning skills: the student will develop the skills necessary to continue their studies with a high degree of autonomy. The achieved preparation can allow the insertion in the various areas of work.


Passing examinations in General Chemistry, Organic Chemistry, Physical Chemistry and Biochemistry is mandatory.


The economic importance and characteristics of the Chemical Industry.Green Chemistry. Envisioning the process : conversion, efficiency and yield. Evaluation of a reaction : economic and technical feasibility.
The material balance equation. Representation of material flow in a chemical process. The energy balance.Numerical exercises.
Catalysis. Homogeneous catalysis. Acid-base catalysis. Heterogeneous catalysis.Classification of catalysts, Acid solids catalysts. Kinetic of the heterogeneous catalytic reactions.
Biocatalysis : the enzymes.
Enzymes preparation for catalytic use.
Bioconversion and biotrasformation.
Immobilized enzymes. Water activity.
Reactions catalysed by enzimes.
The reactors.
Heat transfer : conduction and convection. Heat exchange arrangements.
Separation process. Characteristics of separation process. Selection of a separation process.
Biotechnology and the base chemistry. Polymer and biopolymer.
Biotechnology and the renewable energy.
Laboratory training:
Use of gas chromatography for analytical determinations.
Assessment of the acidity of a solid catalyst by the Benesi method.
A case study of a catalytic reaction in liquid phase.
Polymerization reactions: A) preparation of a linear polyester; B) preparation of a polyester mesh; C) nylon 6-6 synthesis.
Xylene isomers separation by fractional crystallization and distillation.

Teaching Methods

The course includes 32 hours of lectures, 12 hours of numerical exercises; 24 hours of laboratory exercises.

Verification of learning

The profit exam is for a written test and an oral exam. The written test consists of the resolution of three numerical exercises relating to: conversion, selectivity, yield, atomic economy and atomic efficiency of a reaction, material balance, heat transfer, and three open questions on the subjects covered. The oral test addresses All the topics covered, the exercises that are the subject of the written test, and the reports of laboratory exercises. The final vote is expressed in thirty-five as a sum of the votes obtained in the written test (max 10 points) and in the oral exam (max 20 points). To be able to take the oral exam, the written test must be passed by a vote of at least 6 / 10. The written test is valid for one year.
The final vote takes into account several factors:
A) Expressive ability;
B) Knowledge of the scientific language relevant to the course;
C) Baggage of possessed possessions;
D) The ability to link the notions and place them within a logical framework;
E) The ability to connect different frameworks by finding common points and establishing a coherent overall design;
F) Ability to express notions and concepts graphically in the form of, for example, formulas, schemes, equations.
Consequently, judgment may be:
A) Sufficient (from 18 to 20/30)
The candidate demonstrates modest, but still sufficient, capacity to support a coherent dialogue. Few lessons learned, superficial level, many gaps, and elementary conceptual connections. Graphic expression rather stunted;
B) Fair (21 to 23)
The candidate demonstrates more expressive skills than sufficient to support a coherent dialogue. Acceptable mastery of scientific language. Discreet acquisition of notions, but little depth, few gaps, and conceptual connections of moderate complexity. Acceptable graphic expression capability;
C) Good (from 24 to 26)
The candidate demonstrates satisfactory expressive skills and significant mastery of the scientific language. Baggage of rather broad, moderate insight, with little gaps. Dialogical capacity and critical spirit well-perceived. Graphic expression capability more than acceptable;
D) Great (from 27 to 29)
The candidate demonstrates remarkable expressive abilities and a high level of mastery of scientific language. Baggage of very extensive, thorough knowledge, with marginal lacks. Significant dialogic capacity, good competence, and considerable aptitude for logical synthesis. High graphic expression capability;
E) Excellent (30)
The candidate demonstrates high expressive skills and a high level of mastery of scientific language. Baggage of very extensive and in-depth knowledge, any irrelevant gaps. Excellent dialogic capacity, a strong ability to make connections between different topics. Great acquaintance with graphic expression.
Praise is given to candidates well above the average, and whose possible expressive, notional, conceptual, and logical limits appear to be totally irrelevant.


1. Clausen- Mattson “ Principles of Industrial Chemistry, Ed. John Wiley & Sons ( 1978 )
2. Carrà – Morbidelli “ Chimica Fisica Applicata “ Ed. Hoepli ( 1983 )
3.Smith “ Biotecnologie “ Ed. Zanichelli ( 1998 );
4. Alberghina, Cernia “ Biotecnologie e Bioindustria “ Ed. Utet ( 1996 ) ;
5. Straathof “ Applied Biocatalysis “ Harwood Academic Publishers ( 2000 ) ;
6. Petrone “ Biotecnologia” Ed. Siderea ( 2000 );
7. Verga, Pilone “ Biochimica Industriale “ Ed. Springer ( 2002 )

More Information

The students have at their disposal:
the slides of the lectures;
copy of the record of numerical exercises with solutions;
copy of the texts of the task of examination.

Questionnaire and social

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