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Second Semester 
Teaching style
Lingua Insegnamento

Informazioni aggiuntive

Course Curriculum CFU Length(h)
[60/56]  INDUSTRIAL BIOTECHNOLOGY [60/56-00 - Ord. 2013]  PERCORSO COMUNE 7 68


Knowledge:the course aims to provide basic knowledge pertaining to the implementation and conduct of chemical and biotechnological processes applied to industry with references to the information of the basic chemistry and information on economic choices and sustainable development compatible.
Capacity:the student will be able to use the acquired knowledge to a practical application in analysis laboratories and research and management of industrial biotechnology processes.
Skills: the student should acquire: dexterity than the instruments and equipment in industrial chemistry;autonomy and practice in conducting laboratory experiments; ability to work constructively in groups.


Passing examinations in General Chemistry, Organic Chemistry, Physical Chemistry and Biochemistry is mandatory.


The economic importance and characteristics of the Chemical Industry. Envisioning the process : conversion, efficiency and yield. Evaluation of a reaction : economic and technical feasibility.
The material balance equation. Representation of material flow in a chemical process. The energy balance.Numerical exercises.
Catalysis. Homogeneous catalysis. Acid-base catalysis. Heterogeneous catalysis.Classification of catalysts, Acid solids catalysts. Kinetic of the heterogeneous catalytic reactions.
Biocatalysis : the enzymes.
Enzymes preparation for catalytic use.
Bioconversion and biotrasformation.
Immobilized enzymes. Water activity.
Reactions catalysed by enzimes : oxidoreductases,transferases,hydrolases, lyases,isomerases,ligases.
Heat transfer : conduction and convection. Heat exchange arrangements.
Separation process. Characteristics of separation process. Selection of a separation process.
Fractional distillation, crystallization, filtration, chromatography, centrifugation.
Biotechnology and the base chemistry. Polymer and biopolymer.
Biotechnology and the fine chemistry: enzymes, aminoacids, vitamins.
Biotechnology and the alimentary industry.
Biotechnology and the environment.
Biotechnology and the renewable energy.
Laboratory training:
Use of gas chromatography for analytical determinations.
Assessment of the acidity of a solid catalyst by the Benesi method.
A case study of a catalytic reaction in liquid phase.
Polymerization reactions: A) preparation of a linear polyester; B) preparation of a polyester mesh; C) nylon 6-6 synthesis.
Xylene isomers separation by fractional crystallization and distillation.

Teaching Methods

The course includes 32 hours of lectures, 12 hours of numerical exercises; 24 hours of laboratory exercises.

Verification of learning

The exam consists of a written test regarding the resolution of numerical exercises pertaining to the program being performed and an oral examination of all the topics, exercises on the subject of the written test and on the reports of laboratory exercises.
The final vote, express in trentesimi, keeps in mind of the quality of the knowledges, ability, competences possessed e/o manifested e/o. The final vote keeps in mind besides expressive ability, of the appropriate use of the specific language of the discipline, of the logical abilities in the link of the contents.


1. Clausen- Mattson “ Principles of Industrial Chemistry, Ed. John Wiley & Sons ( 1978 )
2. Carrà – Morbidelli “ Chimica Fisica Applicata “ Ed. Hoepli ( 1983 )
3.Smith “ Biotecnologie “ Ed. Zanichelli ( 1998 );
4. Alberghina, Cernia “ Biotecnologie e Bioindustria “ Ed. Utet ( 1996 ) ;
5. Straathof “ Applied Biocatalysis “ Harwood Academic Publishers ( 2000 ) ;
6. Petrone “ Biotecnologia” Ed. Siderea ( 2000 );
7. Verga, Pilone “ Biochimica Industriale “ Ed. Springer ( 2002 )

More Information

The students have at their disposal:
the slides of the lectures;
copy of the record of numerical exercises with solutions;
copy of the texts of the task of examination.

Questionnaire and social

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