Title:  Stimulation of DNA synthesis after a single administration of cadmium nitrate.
Internal authors: 
Issue Date:  1984
Journal: 
TOXICOLOGY LETTERS  
Abstract:  The effect of a single intravenous (i.v.) injection of cadmium nitrate was investigated in livers of male Wistar rats. A significant increase in liver weight, accompanied by an elevation of total hepatic DNA content was observed. DNA synthesis as measured by the incorporation of [3H]thymidine, was found to be 6 times greater than the control, at 24 h after treatment, and remained elevated over a period of 72 h. This elevation in DNA synthesis was not a consequence of cell necrosis, since no increase of serum glutamate-pyruvate transaminase (SGPT) activity was observed.
URI:  http://hdl.handle.net/11584/103725
Type: 1.1 Articolo in rivista

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