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Title Issue Date Author(s) Journal Publisher
The thyromimetic KB2115 (Eprotirome) induces rat hepatocyte proliferation 2017 Szydlowska, Marta; Pibiri, Monica; Perra, Andrea; Puliga, Elisabetta; Mattu, Sandra; Ledda, GIOVA...NNA MARIA; Columbano, Amedeo; Leoni, VERA PIERA GENE EXPRESSION
Induction of autophagy promotes the growth of early preneoplastic rat liver nodules 2016 Kowalik, MA; Perra, A; Ledda-Columbano, GM; Ippolito, G; Piacentini, M; Columbano, A; Falasca, L ONCOTARGET
Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis 2016 Kowalik, Marta Anna; Guzzo, Giulia; Morandi, Andrea; Perra, Andrea; Menegon, Silvia; Masgras, Ion...ica; Trevisan, Elena; Angioni, Maria Maddalena; Fornari, Francesca; Quagliata, Luca; Ledda-Columbano, Giovanna Maria; Gramantieri, Laura; Terracciano, Luigi; Giordano, Silvia; Chiarugi, Paola; Rasola, Andrea; Columbano, Amedeo ONCOTARGET
The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival 2016 Mattu, S; Fornari, F; Quagliata, L; Perra, Andrea; Angioni, MARIA MADDALENA; Petrelli, A; Menegon..., S; Morandi, A; Chiarugi, P; Ledda, GIOVANNA MARIA; Gramantieri, L; Terracciano, L; Giordano, S; Columbano, Amedeo JOURNAL OF HEPATOLOGY
Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis 2015 Kowalik, MA; Sulas, P; Ledda-Columbano, GM; Giordano, S; Columbano, A; Perra, A ONCOTARGET
Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats 2015 Frau C; Loi R; Petrelli A; Perra A; Menegon S; Kowalik M A; Pinna S; Leoni V P; Fornari F; Graman...tieri L; Ledda-Columbano G M; Giordano S; Columbano A HEPATOLOGY
Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis 2015 Zavattari, Patrizia; Perra, Andrea; Menegon, S; Kowalik, MARTA ANNA; Petrelli, A; Angioni, MARIA... MADDALENA; Follenzi, A; Quagliata, L; Ledda, GIOVANNA MARIA; Terracciano, L; Giordano, S; Columbano, Amedeo HEPATOLOGY
MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC). 2014 Petrelli, A; Perra, Andrea; Cora, D; Sulas, P; Menegon, S; Manca, C; Migliore, C; Kowalik, MARTA ... ANNA; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo HEPATOLOGY
Triiodothyronine induces hepatocyte proliferation by protein kinase A-dependent-b-catenin activation in rodents. 2014 Fanti M; Singh S; Ledda-Columbano G M; Columbano A; Monga S P HEPATOLOGY
Timed regulation of P-element-induced wimpy testis-interacting RNA expression during rat liver regeneration 2014 Rizzo, F; Hashim, A; Marchese, G; Ravo, M; Tarallo, R; Nassa, G; Giurato, G; Rinaldi, A; Cordella..., A; Persico, M; Sulas, P; Perra, A; Ledda-Columbano, GM; Columbano, A; Weisz, A HEPATOLOGY
YAP activation is an early event and a potential therapeutic target in liver cancer development 2014 Perra, Andrea; Kowalik, MARTA ANNA; Ghiso, E; Ledda, GIOVANNA MARIA; Di Tommaso, L; Angioni, MAR...IA MADDALENA; Raschioni, C; Testore, E; Roncalli, M; Giordano, S; Columbano, Amedeo JOURNAL OF HEPATOLOGY
Transcription profiling by array of mouse liver from TCPOBOP treated wild type and c-jun conditional knockout animals. 2012 Leoni VP; Ledda-Columbano GM; Pibiri M; Saliba C; Perra A; Kowalik MA; Grober Oli MV; Ravo M; A; Ghiso E; Giordano S; Columbano A
Sequential analysis of multistage hepatocarcinogenesis reveals that miR-100 and PLK1 dysregulation is an early event maintained along tumor progression 2012 Petrelli A; Perra A; Schernhuber K; Cargnelutti M; Salvi A; Migliore C; Ghiso E; Benetti A; Barla...ti S; Ledda-Columbano GM; Portolani N; De Petro G; Columbano A; Giordano S ONCOGENE
Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in mice 2011 Tian J; Huang H; Hoffman B; Liebermann D A; Ledda-Columbano G M; Columbano A; Locker J THE JOURNAL OF CLINICAL INVESTIGATION
Reply to: Clinical correlation of miR-375 and alpha-fetoprotein in hepatocellular carcinoma: comparison in mice and humans 2011 Kowalik, MARTA ANNA; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo HEPATOLOGY
Proteomic characterization of early changes induced by triiodothyronine in rat liver 2011 Severino, V; Locker, J; Ledda, GIOVANNA MARIA; Columbano, Amedeo; Parente, A; Chambery, A. JOURNAL OF PROTEOME RESEARCH
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice 2011 Kowalik, MARTA ANNA; Saliba, C; Pibiri, Monica; Perra, Andrea; Ledda, GIOVANNA MARIA; Sarotto, I;... Ghiso, E; Giordano, S; Columbano, Amedeo HEPATOLOGY
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3 2011 Leoni, VERA PIERA; Ledda, GIOVANNA MARIA; Pibiri, Monica; Saliba, C; Perra, Andrea; Kowalik, MART...A ANNA; Grober, Om; Ravo, M; Weisz, A; Locker, J; Ghiso, E; Giordano, S; Columbano, Amedeo JOURNAL OF HEPATOLOGY
TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells 2010 Kowalik MA; Perra A; Pibiri M; Cocco MT; Samarut J; Plateroti M; Ledda-Columbano GM; Columbano A JOURNAL OF HEPATOLOGY
Progenitor-derived hepatocellular carcinoma model in the rat 2010 Andersen JB; Loi R; Perra A; Factor VM; Ledda-Columbano GM; Columbano A; Thorgeirsson SS. HEPATOLOGY

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