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Title Issue Date Author(s) Journal Publisher
Gender Differences in the Outcome of Offspring Prenatally Exposed to Drugs of Abuse 2020 Traccis, Francesco; Frau, Roberto; Melis, Miriam FRONTIERS IN BEHAVIORAL NEUROSCIENCE
5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction 2019 Fanni, S; Scheggi, S; Rossi, F; Tronci, E; Traccis, F; Stancampiano, R; DE MONTIS, MARIA GRAZIELL...A; Devoto, P; Gambarana, C; Bortolato, M; Frau, R; Carta, M NEUROBIOLOGY OF DISEASE
Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats 2019 Frau, R; Bortolato, M NEUROPHARMACOLOGY
Dysfunctional mesocortical dopamine circuit at pre-adolescence is associated to aggressive behavior in MAO-A hypomorphic mice exposed to early life stress 2019 Frau, Roberto; Fanni, Silvia; Serra, Valeria; Simola, Nicola; Godar, Sean; Traccis, Francesco; De...voto, Paola; Bortolato, Marco; Melis, Miriam NEUROPHARMACOLOGY
Gene-environment interactions in antisocial behavior are mediated by early-life 5-HT2A receptor activation 2019 Godar, Sean C; Mosher, Laura J; Scheggi, Simona; Devoto, Paola; Moench, Kelly M; Strathman, Hunte...r J; Jones, Cori M; Frau, Roberto; Melis, Miriam; Gambarana, Carla; Wilkinson, Brent; DeMontis, M Graziella; Fowler, Stephen C; Coba, Marcelo P; Wellman, Cara L; Shih, Jean C; Bortolato, Marco NEUROPHARMACOLOGY
The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia 2019 De Felice, M.; Melis, M.; Aroni, S.; Muntoni, A. L.; Fanni, S.; Frau, R.; Devoto, P.; Pistis, M. CNS NEUROSCIENCE & THERAPEUTICS
Startle Reflex as a possible biomarker associated with REM sleep behavior disorders in the prodromal stage of Parkinson's disease 2019 Traccis, F; Puligheddu, M; Figorilli, M; Carta, M; Devoto, P; Giua, G; Fantini, ML; Pani, D; Bort...olato, M; Frau, R MOVEMENT DISORDERS
Modulation of the Startle Response in REM Sleep Behavior Disorder 2019 Puligheddu, M; Figorilli, M; Fantini, ML; Carta, M; Traccis, F; Frau, R; Devoto, P; Pani, D; Bort...olato, M MOVEMENT DISORDERS
Sleep in Parkinson’s Disease with Impulse Control Disorder 2018 Figorilli, Michela; Congiu, Patrizia; Lecca, Rosa; Gioi, Gioia; Frau, Roberto; Puligheddu, Monica CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
The neurosteroidogenic enzyme 5α-reductase mediates psychotic-like complications of sleep deprivation 2017 Frau, Roberto; Bini, Valentina; Soggiu, Alessio; Scheggi, Simona; Pardu, Alessandra; Fanni, Silvi...a; Roncada, Paola; Puligheddu, MONICA MARIA FRANCESCA; Marrosu, Francesco; Caruso, Donatella; Devoto, Paola; Bortolato, Marco NEUROPSYCHOPHARMACOLOGY
New vistas on cannabis use disorder 2017 Melis, Miriam; Frau, Roberto; Kalivas, Peter W.; Spencer, Sade; Chioma, Vivian; Zamberletti, Eric...a; Rubino, Tiziana; Parolaro, Daniela NEUROPHARMACOLOGY
The 5-alpha reductase inhibitor finasteride reduces dyskinesia in a rat model of Parkinson's disease 2017 Roberto, Frau; Paola, Savoia; Silvia, Fanni; Chiara, Fiorentini; Camino, Fidalgo; Elisabetta, Tro...nci; Roberto, Stancampiano; Mario, Meloni; Antonino, Cannas; Francesco, Marrosu; Marco, Bortolato; Paola, Devoto; Cristina, Missale; Manolo, Carta EXPERIMENTAL NEUROLOGY
Selective activation of D1 dopamine receptors impairs sensorimotor gating in Long-Evans rats 2016 Mosher, L.J.; Frau, R.; Pardu, A.; Pes, R.; Devoto, P.; Bortolato, M. BRITISH JOURNAL OF PHARMACOLOGY
Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation 2016 Devoto, P; Fattore, L; Antinori, S; Saba, P; Frau, R; Fratta, W; Gessa, GL ADDICTION BIOLOGY
Effects of maternal immune activation on dopamine activity in male and female offspring 2016 De Felice, M.; Aroni, S.; Muntoni, A. L.; Frau, R.; Fanni, S.; Pardu, A.; Devoto, P.; Pistis, M. EUROPEAN NEUROPSYCHOPHARMACOLOGY
The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating 2016 Frau, R; Mosher, LJ; Bini, V; Pillolla, G; Pes, R; Saba, P; Fanni, S; Devoto, P; Bortolato, M PSYCHONEUROENDOCRINOLOGY
Maternal immune activation disrupts dopamine system in the offspring 2016 Luchicchi, A; Lecca, S; Melis, M; De Felice, M; Cadeddu, F; Frau, R; Muntoni, AL; Fadda, P; Devot...o, P; Pistis, M INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress 2015 Frau, R.; Abbiati, F.; Bini, V.; Casti, A.; Caruso, D.; Devoto, P.; Bortolato, M. SCHIZOPHRENIA RESEARCH
Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex 2015 Devoto, Paola; Flore, Giovanna; Saba, Pierluigi; Frau, Roberto; Gessa, Gian L. BRAIN AND BEHAVIOR
Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation 2014 Frau, R; Bini, V; Pes, R; Pillolla, G; Saba, P; Devoto, P; Bortolato, M PSYCHONEUROENDOCRINOLOGY
Juvenile cannabinoid treatment induces frontostriatal gliogenesis in Lewis rats 2014 Bortolato, M; Bini, V; Frau, R; Devoto, P; Pardu, A; Fan, Y; Solbrig, MV EUROPEAN NEUROPSYCHOPHARMACOLOGY
Positive allosteric modulation of GABAB receptors ameliorates sensorimotor gating in rodent models 2014 Frau, R; Bini, V; Pillolla, G; Malherbe, P; Pardu, A; Thomas, AW; Devoto, P; Bortolato, M CNS NEUROSCIENCE & THERAPEUTICS
The steroid 5-alpha reductases mediate the abnormalities in information processing and attention mechanisms induced by REM sleep deprivation 2013 FRAU R; Bini V; Abbiati F; Soggiu A; Caruso D; Roncada P; Devoto P; Bortolato M
PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. 2013 Melis M; Scheggi S; Carta G; Madeddu C; Lecca S; Luchicchi A; Cadeddu F; Frau R; Fattore L; Fadda... P; Ennas MG; Castelli MP; Fratta W; Schilstrom B; Banni S; De Montis MG; Pistis M THE JOURNAL OF NEUROSCIENCE
Allopregnanolone mediates manic-like outcomes of REM sleep deprivation 2013 Frau R; Bini V; Pardu A; Pes R; Abbiati F; Soggiu A; Roncada P; Caruso D; Devoto P; Bortolato M
Allopregnanolone mediates manic-like outcomes of REM sleep deprivation 2013 Frau R; Bini V; Pardu A; Pes R; Abbiati F; Soggiu A; Roncada P; Caruso D; Devoto P; Bortolato M
The implication of neuroactive steroids in tourette's syndrome pathogenesis: A role for 5α-reductase? 2013 Bortolato, M; Frau, Roberto; Godar, Sc; Mosher, Lj; Paba, S; Marrosu, Francesco; Devoto, Paola JOURNAL OF NEUROENDOCRINOLOGY
Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice 2013 Frau, Roberto; Pillolla, Giuliano; Bini, V; Tambaro, S; Devoto, Paola; Bortolato, M. PSYCHONEUROENDOCRINOLOGY
Regional distribution of 5α-reductase type 2 in the adult rat brain: An immunohistochemical analysis 2013 Castelli, MARIA PAOLA; Casti, Alberto; Casu, A; Frau, Roberto; Bortolato, M; Spiga, Saturnino; En...nas, MARIA GRAZIA PSYCHONEUROENDOCRINOLOGY
Chronic tryptophan deprivation attenuates gating deficits induced by 5-HT 1A, but not 5-HT 2 receptor activation 2013 Stancampiano, Roberto; Frau, Roberto; Bini, V; Collu, Maria; Carta, Manolo; Fadda, F; Bortolato, M. EUROPEAN NEUROPSYCHOPHARMACOLOGY
Antipsychotic-like properties of antiandrogenic drugs: focus on dopaminergic system 2013 Frau R; Bini V; Devoto P; Bortolato M
Positive Allosteric modulation of GABA-B receptors: a novel therapeutic approach for schizophrenia 2013 FRAU R
Reserpine treatment ablates the deficits of sensorimotor gating induced by dopamine D3 receptor activation in Sprague-Dawley, but not Long-Evans rats 2013 Mosher L; Frau R; Godar S; Devoto P; Bortolato M
Role of Neurosteroids in dopamine-stress interactions 2012 Frau R
Inhibition of steroid 5-alpha reductase reduces marble-burying responses in mice 2012 Bini V; FRAU R; Paba S; Collu M; Castelli MP; Devoto P; Bortolato M
NMDA receptors mediate the role of monoamine oxidase A in pathological aggression 2012 Godar SC; Bortolato M; Melis M; Soggiu A; Roncada P; Casu A; Flore G; Chen K; FRAU R; Urbani A; C...astelli MP; Devoto P; Shih JC SOCIETY FOR NEUROSCIENCE
Inhibition of 5 alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation 2012 Devoto, Paola; Frau, Roberto; Bini, V; Pillolla, Giuliano; Saba, Pierluigi; Flore, Giovanna; Coro...na, M; Marrosu, Francesco; Bortolato, M. PSYCHONEUROENDOCRINOLOGY
NMDARs mediate the role of monoamine oxidase A in pathological aggression 2012 Bortolato, M; Godar, Sc; Melis, Miriam; Soggiu, A; Roncada, P; Casu, A; Flore, G; Chen, K; Frau, ...Roberto; Urbani, A; Castelli, MARIA PAOLA; Devoto, Paola; Shih, Jc THE JOURNAL OF NEUROSCIENCE
Administration of finasteride modulates depressive-like behavior in the forced swim task of male rats 2012 Koonce CJ; Walf AA; FRAU R; Bini V; Bortolato M; Frye CA 42nd annual meeting of the Society of Neuroscience
Dopamine-beta-hydroxylase inhibition potentiates cocaine effect on dopamine release in the medial prefrontal cortex 2012 Devoto P; FRAU R; Fattore L; Fratta W; Gessa GL
Reversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice 2012 Marongiu, Mfranca; Poddie, D; Porcu, S; Manchinu, Mf; Castelli, MARIA PAOLA; Sogos, Valeria; Bini..., V; Frau, Roberto; Caredda, E; Collu, Maria; Ristaldi, Ms PLOS ONE
Localisation of steroid 5α-reductase type 2 isoenzyme in the adult rat brain 2011 Casti A; Casu P; Casti P; Frau R; Bortolato M; Spiga S; Castelli M; Ennas MG
Localization of steroid 5α-reductase type 2 isozyme in the adult rat brain 2011 Casti A; Casu A; Casti P; FRAU R; Bortolato M; Spiga S; Castelli MP; Ennas MG SfN
Localization of steroid 5α-reductase type 2 isozyme in the adult rat brain. 2011 CASTI A; CASU A; CASTI P; FRAU R; BORTOLATO M; SPIGA S; CASTELLI M; ENNAS M Society for Neuroscience
Steroid 5 alpha-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders 2011 Paba, S; Frau, Roberto; Godar, Sc; Devoto, Paola; Marrosu, Francesco; Bortolato, M. CURRENT PHARMACEUTICAL DESIGN
Isolation rearing-induced reduction of brain 5 alpha-reductase expression: Relevance to dopaminergic impairments 2011 Bortolato, M; Devoto, Paola; Roncada, P; Frau, Roberto; Flore, G; Saba, Pierluigi; Pistritto, G; ...Soggiu, A; Pisanu, S; Zappala, A; Ristaldi, Ms; Tattoli, M; Cuomo, V; Marrosu, Francesco; Barbaccia, Ml NEUROPHARMACOLOGY
Inhibition of 5α-reductase counters the behavioral effects of D1, but not D2 dopamine receptor activation 2011 FRAU R; Bini C; Pillolla G; Tambaro S; Bortolato M; Devoto P Society of Neuroscience (SfN)
5-alpha reductase expression is reduced in brain of isolation-reared rats: relevance to dopaminergic impairments 2011 Devoto P; FRAU R; Bini V; Pillolla G; Paba S; Bortolato M 6th International Meeting of Steroids and Nervous System
Chronic CB1 receptor antagonism induces sensitization to the anxiogenic effects of cannabinoids 2011 Tambaro S; FRAU R; Bini V; Bortolato M SfN
Inhibition of 5-alpha reductase elicits antipsychotic-like effects via post-synaptic mechyanisms in nucleus accumbens and prefrontal cortex 2011 FRAU R; Bortolato M; Bini V; Pillolla G; Paba S; Devoto P 6th International Meeting of Steroids and Nervous System

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