Select Academic Year:     2016/2017 2017/2018 2018/2019 2019/2020 2020/2021 2021/2022
Professor
GIOVANNA LUCIA DELOGU (Tit.)
Period
First Semester 
Teaching style
Convenzionale 
Lingua Insegnamento
 



Informazioni aggiuntive

Course Curriculum CFU Length(h)
[50/22]  PHARMACY [22/00 - Ord. 2020]  PERCORSO COMUNE 10 80

Objectives

Good knowledge of general organic chemistry, based on the understanding of the atomic structure of the carbon atom as described by a simple approach through quantum mechanics; application of this knowledge to bond formation in organic derivatives, origin of chirality and geometrical isomerism; ability to draw and read chiral center(s) following main conventions; knowledge of the main rules of IUPAC nomenclature and ability to use them, Understanding of the V.B. and M.O. methods and of the theory of resonance; main theories of acidity and their applications on organic derivatives; knowledge of the concept of functional group and its utilization in organic chemistry; knowledge of the main mechanisms of organic reactions (radical, SN1, SN2, E1, E2) as well as the mechanisms of electrophilic and nucleophilic reactions in aromatic and carbonyl systems; mechanisms and utilization of the main condensation reactions of carbonyl compounds; knowledge of the main C-C bond formation reactions, which utilize organometallic compounds; a general knowledge of the occurrence of organic derivatives in nature and comprehension of the principal reactions of the following functional groups: alkanes, alkenes, alkines, dienes, haloalkanes, benzene, alcohols and phenols, ethers and epoxides, aldheydes and ketones, carboxylic acids and their derivatives, amines, furan pyrrol, thiophene and pyridine;

Prerequisites

Knowledge of general and inorganic chemistry (main elements).

Contents

1) Reminds of basic knowledges on atomic structure and chemical bond theory (V.B and M.O.); Lewis structures, resonance structures, geometric structure of the organic molecules as a function of C hybridization; hints of Brønsted-Lowry and Lewis acid theories.
2) Drawing of chemical structures and their utility, concept of functional group and their nomenclature.
3) The molecule of methane as an example of alkanes structure and reactivity, its radical reaction with halogens including mechanism, energetic parameters and structure of the methyl radical.
4) Alkanes, generality; Newton formulas, main reactions and main preparative methods.
5) Carbon stereochemistry and stereoisomery; chiral carbon, enantiomers and diastereoisomers, Newton formulas, Cahn-Ingold-Prelog convention.
6) Aloalkanes, their nucleophilic reactions (SN1 and SN2), formation and stability of carbocations.
7) Alcohols, generality; main reactions and main preparative methods; ethers and epoxides generality; main reactions and main preparative methods.
8) Alkenes, generality; main reactions and main preparative methods; E/Z isomers; E1 and E2 reactions, including details of their stereochemistry, (stereoselection and stereospecificity) radical and Ziegler-Natta polimerizations.
9) Alkynes, generality; main reactions and main preparative methods.
10) Cycloalkanes, generality; stereochemistry and conformation analysis in cyclohexane;
11) Benzene, generality; aromaticity and Hückel rule; electrophilic aromatic substitution;
12) Arenes, generality; main reactions and main preparative methods; nucleophilic aromatic substitution
13) Aldehydes and ketones, generality; main reactions (Wittig reaction included) and main preparative methods;
14) Carboxylic acids and their functional derivatives, generality; main reactions and main preparative methods;
15) Amines, generality; main reactions and main preparative methods; aromatic heterocyclic compounds. hints on Pyrrole, Furan, Thiophene and Pyridine;
16) Phenols, generality; main reactions and main preparative methods;
17) ; a-ß-unsaturated carbonyl compounds and conjugated systems, main reactions;

Teaching Methods

The teaching will be delivered simultaneously both in presence and online. Mixed teaching available in university classrooms but at the same time also at a distance. The student can choose in a binding way, for face-to-face or distance teaching.
Front lessons (74 hours) and exercises with the teacher (14 hours)

Verification of learning

Written examination, followed by its oral discussion.
The final grade takes into account several factors:
1) Quality of the knowledge, skills, competences;
2) communication skills;
3) availability to exchange and interaction with the teacher during the interview.
The judgment can be:
a) Enough (18 to 20/30)
The candidate demonstrates little acquisition of theoretical knowledge, superficial level, many gaps; modest communicative abilities, but still sufficient to support a coherent dialogue, logical capacity and consequentiality in fitting the topics of elementary level; poor capacity of synthesis and rather stunted ability of graphical expression, scanty interaction with the teacher during interview.
b) Moderate (21 to 23)
The candidate demonstrates a moderate acquisition of knowledge but lack of deepening, a few gaps; communicative abilities more than sufficient to support a coherent dialogue; acceptable mastery of the scientific language, logical capacity and consequentiality in fitting the topics of moderate complexity, good enough capacity of synthesis and acceptable ability to graphic expression.
c) Good (24 to 26)
The candidate demonstrates a rather large wealth of knowledge, moderate deepening, with small gaps; satisfactory mastery of the communicative abilities and meaningful scientific language, dialogue capabilities and critical thinking well detectable, good capacity for synthesis and more than acceptable ability to graphic expression.
d) Outstanding (27 to 29)
The candidate demonstrates a very extensive wealth of notions, high in-depth, with marginal gaps; remarkable ability in communicating and high mastery of scientific language; remarkable dialogue capacity, good competence and relevant aptitude for logical synthesis, high capacity of synthesis and graphical expression.
e) Excellent (30)
The candidate demonstrates a wealth of very extensive and in-depth knowledge, irrelevant gaps, high capacity and high mastery in communicating through the scientific language, excellent dialogue capabilities, and marked aptitude to make connections among different topics, excellent ability to synthesize and very familiar with the graphical expression.
The praise is attributed to the candidates clearly above average, and whose notional, expressive, conceptual, logical limits, if any, as a whole are completely irrelevant

Texts

Chimica Organica – Bruice EdiSES
Chimica Organica – Brown-Foote EdiSES



More Information

On request, students may have the slides utilized for course presentation and texts of previous examinations. exercises with a teacher.

Questionnaire and social

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